Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep807 | Nuclear receptors and Signal transduction | ECE2017

Cytotoxic activity of plant extracts from Brazilian biome in prostate cancer cell lines

Cardoso Sarah , Andrade Matheus , Cunha Vinicius , Silva Cristian , Rodrigues Patricia , Leao Mayra , Fagg Christopher , Guerra Eliete , Neves Francisco , Simeoni Luiz , Silveira Damaris , Lofrano-Porto Adriana

Introduction: Prostate cancer is a public health problem worldwide. The cure is unlikely and therapeutic alternatives are limited. The Brazilian biodiversity represents a huge source of potential discovery of new drugs derived from plants. We therefore aimed to conduct a biomonitoring chemical study of plant extracts from Pouteria sp. previously shown to be cytotoxic in androgen-sensitive (LNCaP) and androgen-resistant (PC3) human prostate cancer cell lines.<p cla...